작성자 | Belgebute | ||
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작성일 | 2011-05-11 23:16:08 KST | 조회 | 125 |
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이거 해석좀
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Novel analogues of the angiotensin I-converting enzyme (ACE) inhibitor keto-ACE were synthesized via a facile Horner–Emmons olefination of a phosphonoketone precursor with ethyl glyoxylate. Introduction of a bulky aromatic tryptophan at the position of keto-ACE resulted in a significant increase in C-domain-selectivity.Abstract
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